In addition to epinephrine, what medication is often administered for allergic reactions?

In the management of allergic reactions, especially anaphylaxis, diphenhydramine is often administered alongside epinephrine. Diphenhydramine is an antihistamine that helps block the action of histamine— a substance in the body that can cause allergy symptoms. While epinephrine acts rapidly to counteract the severe effects of anaphylaxis, such as bronchospasm and vasodilation, diphenhydramine can alleviate symptoms like itching, hives, and other mild allergic reactions.

The other medications listed do not serve the same purpose in treating allergic reactions. Aspirin is primarily used for pain relief and reducing inflammation, while ibuprofen also functions as an anti-inflammatory and pain reliever, but neither address histamine-related symptoms. Acetaminophen is mainly used to reduce fever and alleviate pain, and it also does not play a role in counteracting allergic reactions. Therefore, diphenhydramine is the appropriate choice when administered alongside epinephrine for treating allergic reactions.